Abstract Background STAT3 hyper-IgE syndrome (STAT3-HIES) is a rare primary immunodeficiency that clinically overlaps with atopic dermatitis.In addition to eczema, elevated serum-IgE, and recurrent infections, STAT3-HIES patients suffer from characteristic facies, Medical and Ambulatory supplies / Respiratory midline defects, and retained primary t
When exposed to a thermal gradient, reaction networks can convert thermal energy into the chemical selection of states that would be unfavourable at equilibrium.The kinetics of reaction paths, and thus how fast they dissipate available energy, might be dominant in dictating the stationary populations of all chemical states out of equilibrium.This p
A promising open inguinal hernia operation called Onstep was developed in 2005.The technique is BONE STRUCTURE without sutures to the surrounding tissue, causing minimal tension.A specific mesh is used with a memory recoil ring in the border, which may cause pain superficial to the lateral part of the mesh for slender patients.The aim of this study
Abstract Nonreciprocity is important in both optical information processing and topological photonics BONE STRUCTURE studies.Conventional principles for realizing nonreciprocity rely on magnetic fields, spatiotemporal modulation, or nonlinearity.Here we propose a generic principle for generating nonreciprocity by taking advantage of energy loss, wh
Draining peatlands to create agricultural land has been the norm in Europe, but in the context of climate change and the loss of biodiversity, these rich ecosystems may reactivate their functions as greenhouse gas sinks and retreat spaces for animals and plants.Against this background, the National Moor Rewetting Strategy was put into effect in Ger